Search
Advanced Search
Free Shipping on eligible itemsFree Shipping on eligible items
My Cart

Spark Plugs for Lexus IS250

Refine the ignition system of your Lexus IS250 by selecting superior spark plugs for tailored performance. Choose from reliable brands such as E3, which offer exceptional combustion control, or Autolite, known for maintaining engine efficiency. Keep your IS250 running smoothly for every luxurious drive.

Select Your Vehicle

Filter By Part Details
Clear All
View as Grid List

13 Items

Set Ascending Direction
  1. NGK Laser Iridium
    6 pc NGK Laser Iridium Spark Plugs for 2006-2015 Lexus IS250 2.5L V6
    Rating:
    100%
    1  Review
    Special Price $116.24 Regular Price $165.99
    NGK / NTK
  2. DENSO Spark Plug
    6 pc DENSO Iridium TT Spark Plugs for 2006-2015 Lexus IS250 2.5L V6
    Special Price $86.25 Regular Price $122.99
    DENSO
  3. DENSO Spark Plug
    6 pc DENSO Iridium Long Life Spark Plugs for 2006-2015 Lexus IS250 2.5L V6
    Rating:
    100%
    1  Review
    Special Price $117.98 Regular Price $168.99
    DENSO
  4. NGK Spark Plug
    6 pc NGK Ruthenium HX Spark Plugs for 2006-2015 Lexus IS250 2.5L V6
    Special Price $78.32 Regular Price $111.99
    NGK / NTK
  5. Champion Spark Plug
    6 pc Champion Iridium Spark Plugs for 2006-2015 Lexus IS250 2.5L V6
    Special Price $56.12 Regular Price $79.99
    Champion
  6. Champion Spark Plug
    6 pc Champion Copper Plus Spark Plugs for 2006-2015 Lexus IS250 2.5L V6
    Special Price $24.22 Regular Price $34.99
    Champion
  7. Fel-Pro Spark Plug Tube Seal Set
    Fel-Pro Valve Cover Spark Plug Tube Seal Set for 2006-2015 Lexus IS250 2.5L V6
    Special Price $27.32 Regular Price $38.99
    Fel-Pro
  8. Autolite Platinum Spark Plug
    6 pc Autolite Platinum Spark Plug for 2006-2015 Lexus IS250
    Special Price $29.88 Regular Price $42.99
    Autolite
    Out of stock
  9. Autolite Copper Core Spark Plug
    6 pc Autolite Copper Core Spark Plugs for 2006-2015 Lexus IS250
    Special Price $31.16 Regular Price $44.99
    Autolite
    Out of stock
  10. Champion Spark Plug
    6 pc Champion Double Platinum Spark Plugs for 2006-2015 Lexus IS250 2.5L V6
    Special Price $43.61 Regular Price $61.99
    Champion
  11. E3 Spark Plug
    6 pc E3 Spark Plugs for 2006-2015 Lexus IS250 2.5L V6
    Special Price $46.89 Regular Price $66.99
    E3 Spark Plugs
  12. Autolite Double Platinum Spark Plug
    6 pc Autolite Double Platinum Spark Plug for 2006-2015 Lexus IS250
    Special Price $47.40 Regular Price $67.99
    Autolite
    Out of stock
  13. Autolite Iridium XP Spark Plug
    6 pc Autolite Iridium XP Spark Plug for 2006-2015 Lexus IS250
    Special Price $52.24 Regular Price $74.99
    Autolite
    Out of stock
per page

The Sixity Auto Advantage

Finding the right car spark plugs can seem complicated, but our goal is to make it simple. We combine a massive selection of parts from trusted brands with the expert, US-based support you need to make the right choice. With fast shipping and a 100% fitment guarantee, we provide a hassle-free shopping experience that has earned the trust of over a million customers.

Platinum, Iridium, and More

Choosing the right material is key to your engine’s performance and longevity. We carry a massive selection of aftermarket spark plugs in every type, from long-lasting iridium to dependable copper plugs for classic vehicles. Whatever your engine needs, we have the right plug to match its specific requirements, ensuring optimal spark and efficiency.

Expert Support When You Need It

Not sure which plug is right for your vehicle? Our friendly, US-based customer support team is here to help. With deep knowledge of our full catalog, they can guide you to the perfect car spark plugs for your specific make and model. We are committed to helping you buy with confidence and getting your installation done right the first time.

Frequently Asked Questions

Got a question about our automotive spark plugs? Here are a few things people often ask. For anything else, our main FAQ page has you covered.

How do I find the right spark plugs for my car?

Your best bet is our vehicle selector tool. Just plug in your car’s info, and we’ll show you exactly which plugs are guaranteed to work.

Are your aftermarket spark plugs as good as the originals?

Definitely. We only carry parts that are as good or better than the ones that came in your car, but without those dealership prices.

How often should I replace car spark plugs?

That really depends on the type. A standard copper plug is usually good for about 20,000 miles, while a high-end iridium one can last 100,000. Your owner’s manual will have the exact schedule for your engine.

Spark Plug Features

  • Precision ceramic insulators
  • Corrosion-resistant shell with triple high pressure gas seals
  • Screw or snap-on electrical connectors
  • Pre-installed metal compression gaskets
  • Copper-core electrode cooling
  • Application specific heat-range design
  • Improved cold-starting performance
  • Smooth firing at high or low engine RPM
  • Reduced electrode erosion and long service life
  • Enhanced ignition efficiency and fuel economy
  • Superior anti-fouling characteristics
  • Reduced hot-spark firing voltage requirements
  • Maximum engine horsepower and torque
  • Superior throttle-response, acceleration and WOT performance
  • Precision Laser-welded Iridium electrodes - 6X harder than platinum
  • Precision ceramic insulators
  • Corrosion-resistant shell with triple high pressure gas seals
  • Screw or snap-on electrical connectors
  • Pre-installed metal compression gaskets
  • Copper-core electrode cooling
  • Application specific heat-range design
  • Improved cold-starting performance
  • Smooth firing at high or low engine RPM
  • Reduced electrode erosion and long service life
  • Enhanced ignition efficiency and fuel economy
  • Superior anti-fouling characteristics
  • Reduced hot-spark firing voltage requirements
  • Maximum engine horsepower and torque
  • Superior throttle-response, acceleration and WOT performance
  • Precision Laser-welded Iridium electrodes - 6X harder than platinum
free shipping on eligible items at sixityauto.com

FAST & FREE SHIPPING
On eligible items

At SixityAuto.com, we offer free shipping on thousands of eligible items. We also ship FAST. Over 99% of all items ordered will ship within one business day. Plus, we ship from our strategically located warehouses on the East and West Coast to save precious shipping time.

100% fitment guarantee at sixityauto.com

100% FITMENT GUARANTEE
Your parts will fit as advertised

Shop with confidence, knowing that your purchase from Sixity Auto will fit your vehicle. If after purchase you determine that your part does not fit the vehicle we advertised, simply contact us to initiate a return. We want your parts to fit!

5-star customer rated at sitejabber

RAVE REVIEWS
5-Star Rated on Sitejabber

Don't take it from us - check out our feedback from our customers! Sixity Auto has partnered with Sitejabber, the industry leader in tracking customer loyalty and feedback, to bring genuine product and customer service reviews.

Plus read thousands of authentic reviews on Trustpilot, Google, Reseller Ratings, the Better Business Bureau, and more!

call sixity auto 8am to 8pm Eastern, Monday through Friday

WE'RE HERE TO HELP
(888) 679-6279
Monday through Friday, 8am-8pm Eastern

We speak your language. Our staff has decades of experience selling auto parts to enthusiasts like you. Whether it's for your car, truck, or van, we have staff on hand that can answer your questions and make sure you get the part you're looking for.

For phone sales or help with product fitment questions, our U.S.-based customer service staff in California and Indiana is available weekdays, 8am-8pm ET.

tax exempt shopping available for businesses

BUILT FOR BUSINESS
Tax-exempt shopping available

Sixity Auto works with a wide range of business customers—from repair shops and dealerships to fleet operators, government organizations, and others that purchase parts for resale or operational use.

If you are a qualified tax-exempt or resale customer, submit your documentation and we'll set you up for tax-free shopping. Check out all the details here.

military members and vets save 10% every day

MILITARY DISCOUNT
Save 10% on every purchase

Sixity Auto is proud to support our Active-Duty Service Members, Vets, and their immediate families. To show a token of our thanks, we extend a 10% discount on your entire purchase, every single day.

We use VerifyPass (formerly ID Discount) to help us manage our Military Discount program. Click here for all the details!

Sixity PaymentsSixity Payments
A+ Rated by BBBA+ Rated by BBB
SecurityMetrics card safe certification logo

© 2026 Sixity, Inc. Part of Proximity Group, an American-owned and operated online retailer. All Rights Reserved.

© 2026 Sixity, Inc. Part of Proximity Group, an American-owned and operated online retailer. All Rights Reserved.